Syncing with a treo 650 from Ubuntu Edgy: sudo apt-get install pilot-link ( I went ahead and created the device nodes permanently ) sudo mknod /dev/ttyUSB0 188 0 sudo mknod /dev/ttyUSB1 188 1 sudo chmod 777 /dev/ttyUSB* pilot-xfer --port /dev/ttyUSB1 -l How to backup the treo: pilot-xfer --port /dev/ttyUSB1 -b /home/ryan/palmbackup/ How to transfer a file to the treo: ( This one is crazy freaky to figure out with no help ): pilot-xfer -p /dev/ttyUSB3 -D /01_-_Angeltread.mp3 -i ./01_-_Angeltread.mp3 ( How to transfer all mp3s in a directory to the treo ): pilot-xfer -p /dev/ttyUSB1 -D / -i ./*.mp3 NOTE: Notice how sometimes the treo is ttyUSB1 and sometimes ttyUSB3. I don't think it is every responsive on ttyUSB0 or ttyUSB2. Those are probably legacy devices that are not useable.